BDBM50043903 CHEMBL541211::N-Isobutyl-2-(2-oxo-6-sulfamoyl-2,3-dihydro-1H-thieno[2,3-b][1,4]thiazin-3-yl)-acetamide

SMILES: CC(C)CNC(=O)CC1Sc2sc(cc2NC1=O)S(N)(=O)=O

InChI Key: InChIKey=WMLAFWUEOLVYDQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50043903 (CHEMBL541211 | N-Isobutyl-2-(2-oxo-6-sulfamoyl-2,3...) Show SMILES CC(C)CNC(=O)CC1Sc2sc(cc2NC1=O)S(N)(=O)=O Show InChI InChI=1S/C12H17N3O4S3/c1-6(2)5-14-9(16)4-8-11(17)15-7-3-10(22(13,18)19)21-12(7)20-8/h3,6,8H,4-5H2,1-2H3,(H,14,16)(H,15,17)(H2,13,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Tested for ability to compete with dansylamide for binding to human erythrocyte carbonic-anhydrase-II (HCA-II)				J Med Chem 37: 240-7 (1994) BindingDB Entry DOI: 10.7270/Q2N29XKD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50043903 (CHEMBL541211 | N-Isobutyl-2-(2-oxo-6-sulfamoyl-2,3...) Show SMILES CC(C)CNC(=O)CC1Sc2sc(cc2NC1=O)S(N)(=O)=O Show InChI InChI=1S/C12H17N3O4S3/c1-6(2)5-14-9(16)4-8-11(17)15-7-3-10(22(13,18)19)21-12(7)20-8/h3,6,8H,4-5H2,1-2H3,(H,14,16)(H,15,17)(H2,13,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Tested for ability to inhibit human erythrocyte carbonic-anhydrase-II- (HCA II) catalyzed carbon dioxide hydration				J Med Chem 37: 240-7 (1994) BindingDB Entry DOI: 10.7270/Q2N29XKD
					More data for this Ligand-Target Pair