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SMILES: Cc1c[nH]c2ncnc(N3CCC(CC=C)(CC3)C(=O)Nc3cccc(Cl)c3)c12

InChI Key: InChIKey=XIMVZDIPXNUARA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044012   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
LIM domain kinase 2


(Homo sapiens (Human))		BDBM50044012
PNG
(CHEMBL3356424)
Show SMILES Cc1c[nH]c2ncnc(N3CCC(CC=C)(CC3)C(=O)Nc3cccc(Cl)c3)c12
Show InChI InChI=1S/C22H24ClN5O/c1-3-7-22(21(29)27-17-6-4-5-16(23)12-17)8-10-28(11-9-22)20-18-15(2)13-24-19(18)25-14-26-20/h3-6,12-14H,1,7-11H2,2H3,(H,27,29)(H,24,25,26)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Lexicon Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...

ACS Med Chem Lett 6: 84-8 (2015)


Article DOI: 10.1021/ml500367g
BindingDB Entry DOI: 10.7270/Q218384X
More data for this
Ligand-Target Pair