BDBM50044014 CHEMBL3356422
SMILES: C[C@H]1CN(CC[C@@H]1C(=O)Nc1cccc(OC(=O)N(C)C)c1)c1ncnc2[nH]cc(C)c12
InChI Key: InChIKey=VCYAIYACPTUHNX-YJBOKZPZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LIM domain kinase 2 (Homo sapiens (Human)) | BDBM50044014 (CHEMBL3356422) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi... | ACS Med Chem Lett 6: 84-8 (2015) Article DOI: 10.1021/ml500367g BindingDB Entry DOI: 10.7270/Q218384X | |||||||||||
More data for this Ligand-Target Pair |