BDBM50044299 CHEMBL3356907

SMILES: CNC(=O)c1cccc(F)c1Nc1nc(Nc2cccc(NC(=O)CNC(=O)OC(C)(C)C)c2)ncc1Cl

InChI Key: InChIKey=USGJBEWPFUGSJX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50044299 (CHEMBL3356907) Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2cccc(NC(=O)CNC(=O)OC(C)(C)C)c2)ncc1Cl Show InChI InChI=1S/C25H27ClFN7O4/c1-25(2,3)38-24(37)30-13-19(35)31-14-7-5-8-15(11-14)32-23-29-12-17(26)21(34-23)33-20-16(22(36)28-4)9-6-10-18(20)27/h5-12H,13H2,1-4H3,(H,28,36)(H,30,37)(H,31,35)(H2,29,32,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of ALK (unknown origin) after 60 mins by ELISA				J Med Chem 58: 197-211 (2015) Article DOI: 10.1021/jm5005144 BindingDB Entry DOI: 10.7270/Q2FB54MQ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50044299 (CHEMBL3356907) Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2cccc(NC(=O)CNC(=O)OC(C)(C)C)c2)ncc1Cl Show InChI InChI=1S/C25H27ClFN7O4/c1-25(2,3)38-24(37)30-13-19(35)31-14-7-5-8-15(11-14)32-23-29-12-17(26)21(34-23)33-20-16(22(36)28-4)9-6-10-18(20)27/h5-12H,13H2,1-4H3,(H,28,36)(H,30,37)(H,31,35)(H2,29,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) after 60 mins by ELISA				J Med Chem 58: 197-211 (2015) Article DOI: 10.1021/jm5005144 BindingDB Entry DOI: 10.7270/Q2FB54MQ
					More data for this Ligand-Target Pair