Found 5 hits for monomerid = 50044318 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50044318
(CHEMBL305268 | METHANESULFONAMIDE | aminosulfane d...)Show InChI InChI=1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibitory constant against human Carbonic anhydrase I |
Bioorg Med Chem Lett 15: 2353-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.091 BindingDB Entry DOI: 10.7270/Q2KK9CJW |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50044318
(CHEMBL305268 | METHANESULFONAMIDE | aminosulfane d...)Show InChI InChI=1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 3.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibitory constant against human Carbonic anhydrase II |
Bioorg Med Chem Lett 15: 2353-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.091 BindingDB Entry DOI: 10.7270/Q2KK9CJW |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase
(Bos taurus) | BDBM50044318
(CHEMBL305268 | METHANESULFONAMIDE | aminosulfane d...)Show InChI InChI=1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description Inhibition of bovine carbonic anhydrase 2 |
J Med Chem 61: 5822-5880 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01788 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50044318
(CHEMBL305268 | METHANESULFONAMIDE | aminosulfane d...)Show InChI InChI=1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | 1.26E+5 | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description Binding affinity against Carbonic anhydrase II |
J Med Chem 45: 2770-80 (2002)
Article DOI: 10.1021/jm0105833 BindingDB Entry DOI: 10.7270/Q2MG7S8S |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase I
(Homo sapiens (Human)) | BDBM50044318
(CHEMBL305268 | METHANESULFONAMIDE | aminosulfane d...)Show InChI InChI=1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibition of crude dog red blood cell carbonic anhydrase |
J Med Chem 36: 2134-41 (1993)
BindingDB Entry DOI: 10.7270/Q2GX49N1 |
More data for this Ligand-Target Pair | |