BDBM50044365 5-Butyl-2-(2-methoxy-2-phenyl-ethyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL304134

SMILES: CCCCc1nn(CC(OC)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=RDWXWCVXYMAZDM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50044365 (5-Butyl-2-(2-methoxy-2-phenyl-ethyl)-4-[2'-(2H-tet...) Show SMILES CCCCc1nn(CC(OC)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C29H31N7O2/c1-3-4-14-27-32-36(20-26(38-2)23-10-6-5-7-11-23)29(37)35(27)19-21-15-17-22(18-16-21)24-12-8-9-13-25(24)28-30-33-34-31-28/h5-13,15-18,26H,3-4,14,19-20H2,1-2H3,(H,30,31,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Searle R&D Curated by ChEMBL					Assay Description Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranes				J Med Chem 36: 2172-81 (1993) BindingDB Entry DOI: 10.7270/Q2C53JXM
					More data for this Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50044365 (5-Butyl-2-(2-methoxy-2-phenyl-ethyl)-4-[2'-(2H-tet...) Show SMILES CCCCc1nn(CC(OC)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C29H31N7O2/c1-3-4-14-27-32-36(20-26(38-2)23-10-6-5-7-11-23)29(37)35(27)19-21-15-17-22(18-16-21)24-12-8-9-13-25(24)28-30-33-34-31-28/h5-13,15-18,26H,3-4,14,19-20H2,1-2H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranes				Citation and Details Article DOI: 10.1007/s00044-011-9622-4 BindingDB Entry DOI: 10.7270/Q2T156HH
					More data for this Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50044365 (5-Butyl-2-(2-methoxy-2-phenyl-ethyl)-4-[2'-(2H-tet...) Show SMILES CCCCc1nn(CC(OC)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C29H31N7O2/c1-3-4-14-27-32-36(20-26(38-2)23-10-6-5-7-11-23)29(37)35(27)19-21-15-17-22(18-16-21)24-12-8-9-13-25(24)28-30-33-34-31-28/h5-13,15-18,26H,3-4,14,19-20H2,1-2H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranes				Citation and Details Article DOI: 10.1007/s00044-011-9622-4 BindingDB Entry DOI: 10.7270/Q2T156HH
					More data for this Ligand-Target Pair