BDBM50044440 8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL82436

SMILES: O=C1NCN(c2ccccc2)C11CCN(CCCCOc2ccccc2)CC1

InChI Key: InChIKey=TZOSRTSWBQKMTN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044440   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50044440 (8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4....) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CCCCOc2ccccc2)CC1 Show InChI InChI=1S/C23H29N3O2/c27-22-23(26(19-24-22)20-9-3-1-4-10-20)13-16-25(17-14-23)15-7-8-18-28-21-11-5-2-6-12-21/h1-6,9-12H,7-8,13-19H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Tested for binding affinity against 5-hydroxytryptamine 1A receptor from rat frontal cortical regions using [3H]-8-OH-DPAT as radioligand				J Med Chem 36: 2519-25 (1993) BindingDB Entry DOI: 10.7270/Q2QF8RZ9
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50044440 (8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4....) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CCCCOc2ccccc2)CC1 Show InChI InChI=1S/C23H29N3O2/c27-22-23(26(19-24-22)20-9-3-1-4-10-20)13-16-25(17-14-23)15-7-8-18-28-21-11-5-2-6-12-21/h1-6,9-12H,7-8,13-19H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	325	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Tested for binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortical regions using [3H]ketanserin as radioligand				J Med Chem 36: 2519-25 (1993) BindingDB Entry DOI: 10.7270/Q2QF8RZ9
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50044440 (8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4....) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CCCCOc2ccccc2)CC1 Show InChI InChI=1S/C23H29N3O2/c27-22-23(26(19-24-22)20-9-3-1-4-10-20)13-16-25(17-14-23)15-7-8-18-28-21-11-5-2-6-12-21/h1-6,9-12H,7-8,13-19H2,(H,24,27)	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Tested for binding affinity against 5-hydroxytryptamine 1C receptor from rat frontal cortical regions using [3H]-mesulergine as radioligand				J Med Chem 36: 2519-25 (1993) BindingDB Entry DOI: 10.7270/Q2QF8RZ9
					More data for this Ligand-Target Pair