BindingDB logo
myBDB logout

null

SMILES: Cc1nc(Cl)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=ASCOWQDAVUCWHH-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044552   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription factor Jun


(Homo sapiens (Human))		BDBM50044552
PNG
(CHEMBL3341901)
Show SMILES Cc1nc(Cl)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C12H8Cl3N3O/c1-6-10(5-16-12(15)17-6)11(19)18-9-3-7(13)2-8(14)4-9/h2-5H,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay

J Med Chem 57: 6930-48 (2014)


Article DOI: 10.1021/jm5004733
BindingDB Entry DOI: 10.7270/Q2222WDT
More data for this
Ligand-Target Pair