BDBM50044562 CHEMBL3341914
SMILES: CC1=CC(=O)N(Nc2ncc(-c3coc(C)n3)c(n2)-c2cccs2)C1=O
InChI Key: InChIKey=RHBTWDFORLRVLM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Transcription factor AP-1 (Homo sapiens (Human)) | BDBM50044562 (CHEMBL3341914) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch Curated by ChEMBL | Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay | J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT | |||||||||||
More data for this Ligand-Target Pair |