BDBM50044563 CHEMBL3341913

SMILES: CCc1nc(NN2C(=O)C=C(C)C2=O)ncc1-c1coc(C)n1

InChI Key: InChIKey=JHPYMNZPMYYRPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50044563 (CHEMBL3341913) Show SMILES CCc1nc(NN2C(=O)C=C(C)C2=O)ncc1-c1coc(C)n1 |t:9| Show InChI InChI=1S/C15H15N5O3/c1-4-11-10(12-7-23-9(3)17-12)6-16-15(18-11)19-20-13(21)5-8(2)14(20)22/h5-7H,4H2,1-3H3,(H,16,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair