BDBM50044564 CHEMBL315804

SMILES: CC1=CC(=O)N(Nc2ncc(C(=O)c3ccccc3)c(n2)C(F)(F)F)C1=O

InChI Key: InChIKey=GEVKCFZCFWBZDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044564   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50044564 (CHEMBL315804) Show SMILES CC1=CC(=O)N(Nc2ncc(C(=O)c3ccccc3)c(n2)C(F)(F)F)C1=O |t:1| Show InChI InChI=1S/C17H11F3N4O3/c1-9-7-12(25)24(15(9)27)23-16-21-8-11(14(22-16)17(18,19)20)13(26)10-5-3-2-4-6-10/h2-8H,1H3,(H,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair