BDBM50044568 CHEMBL85822

SMILES: CCOC(=O)c1cnc(nc1CC)N(C)N1C(=O)C=C(C)C1=O

InChI Key: InChIKey=WOFXOVURLZJMHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50044568 (CHEMBL85822) Show SMILES CCOC(=O)c1cnc(nc1CC)N(C)N1C(=O)C=C(C)C1=O |t:19| Show InChI InChI=1S/C15H18N4O4/c1-5-11-10(14(22)23-6-2)8-16-15(17-11)18(4)19-12(20)7-9(3)13(19)21/h7-8H,5-6H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair