BDBM50044574 CHEMBL3341910

SMILES: FC(F)(F)c1ccc2Nc3nc(Cl)ncc3C(=O)Nc2c1

InChI Key: InChIKey=WANKECNDCCJFKC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50044574 (CHEMBL3341910) Show SMILES FC(F)(F)c1ccc2Nc3nc(Cl)ncc3C(=O)Nc2c1 Show InChI InChI=1S/C12H6ClF3N4O/c13-11-17-4-6-9(20-11)18-7-2-1-5(12(14,15)16)3-8(7)19-10(6)21/h1-4H,(H,19,21)(H,17,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair