BDBM50044577 CHEMBL3341908

SMILES: FC(F)(F)c1ccc2c(c1)[nH]c(=O)c1cnc(Cl)nc21

InChI Key: InChIKey=POHOVAREWBDFQU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50044577 (CHEMBL3341908) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c(=O)c1cnc(Cl)nc21 Show InChI InChI=1S/C12H5ClF3N3O/c13-11-17-4-7-9(19-11)6-2-1-5(12(14,15)16)3-8(6)18-10(7)20/h1-4H,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair