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BDBM50044578 CHEMBL3341907

SMILES: FC(F)(F)c1cc(CN2C(=O)c3cnc(Cl)nc3C2=O)cc(c1)C(F)(F)F

InChI Key: InChIKey=TXZVQQKOUMZKAA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044578   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription factor AP-1


(Homo sapiens (Human))		BDBM50044578
PNG
(CHEMBL3341907)
Show SMILES FC(F)(F)c1cc(CN2C(=O)c3cnc(Cl)nc3C2=O)cc(c1)C(F)(F)F
Show InChI InChI=1S/C15H6ClF6N3O2/c16-13-23-4-9-10(24-13)12(27)25(11(9)26)5-6-1-7(14(17,18)19)3-8(2-6)15(20,21)22/h1-4H,5H2
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.40E+3n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay

J Med Chem 57: 6930-48 (2014)


Article DOI: 10.1021/jm5004733
BindingDB Entry DOI: 10.7270/Q2222WDT
More data for this
Ligand-Target Pair