BDBM50044581 CHEMBL3341903

SMILES: Cc1cc(nc(Cl)n1)C(=O)Nc1ccc(cc1C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=NBRMGSKUAYPWGT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50044581 (CHEMBL3341903) Show SMILES Cc1cc(nc(Cl)n1)C(=O)Nc1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H8ClF6N3O/c1-6-4-10(24-12(15)22-6)11(25)23-9-3-2-7(13(16,17)18)5-8(9)14(19,20)21/h2-5H,1H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair