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BDBM50044582 CHEMBL3341902

SMILES: FC(F)(F)c1ccc(NC(=O)c2cc(nc(Cl)n2)C(F)(F)F)c(c1)C(F)(F)F

InChI Key: InChIKey=DJMQIHDLROZXOE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044582   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription factor AP-1


(Homo sapiens (Human))		BDBM50044582
PNG
(CHEMBL3341902)
Show SMILES FC(F)(F)c1ccc(NC(=O)c2cc(nc(Cl)n2)C(F)(F)F)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H5ClF9N3O/c15-11-26-8(4-9(27-11)14(22,23)24)10(28)25-7-2-1-5(12(16,17)18)3-6(7)13(19,20)21/h1-4H,(H,25,28)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay

J Med Chem 57: 6930-48 (2014)


Article DOI: 10.1021/jm5004733
BindingDB Entry DOI: 10.7270/Q2222WDT
More data for this
Ligand-Target Pair