BDBM50044646 CHEMBL3309284

SMILES: Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO

InChI Key: InChIKey=FVXNWIVUIWQBNB-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50044646 (CHEMBL3309284) Show SMILES Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C18H23N3O4/c1-21-15-9-7-14(12-13(15)8-10-17(21)23)18(24)19-11-5-3-2-4-6-16(22)20-25/h7-10,12,25H,2-6,11H2,1H3,(H,19,24)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50044646 (CHEMBL3309284) Show SMILES Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C18H23N3O4/c1-21-15-9-7-14(12-13(15)8-10-17(21)23)18(24)19-11-5-3-2-4-6-16(22)20-25/h7-10,12,25H,2-6,11H2,1H3,(H,19,24)(H,20,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC3 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50044646 (CHEMBL3309284) Show SMILES Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C18H23N3O4/c1-21-15-9-7-14(12-13(15)8-10-17(21)23)18(24)19-11-5-3-2-4-6-16(22)20-25/h7-10,12,25H,2-6,11H2,1H3,(H,19,24)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50044646 (CHEMBL3309284) Show SMILES Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C18H23N3O4/c1-21-15-9-7-14(12-13(15)8-10-17(21)23)18(24)19-11-5-3-2-4-6-16(22)20-25/h7-10,12,25H,2-6,11H2,1H3,(H,19,24)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM50044646 (CHEMBL3309284) Show SMILES Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C18H23N3O4/c1-21-15-9-7-14(12-13(15)8-10-17(21)23)18(24)19-11-5-3-2-4-6-16(22)20-25/h7-10,12,25H,2-6,11H2,1H3,(H,19,24)(H,20,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50044646 (CHEMBL3309284) Show SMILES Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C18H23N3O4/c1-21-15-9-7-14(12-13(15)8-10-17(21)23)18(24)19-11-5-3-2-4-6-16(22)20-25/h7-10,12,25H,2-6,11H2,1H3,(H,19,24)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC6 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50044646 (CHEMBL3309284) Show SMILES Cn1c2ccc(cc2ccc1=O)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C18H23N3O4/c1-21-15-9-7-14(12-13(15)8-10-17(21)23)18(24)19-11-5-3-2-4-6-16(22)20-25/h7-10,12,25H,2-6,11H2,1H3,(H,19,24)(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC4 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair