BDBM50044692 3-tert-Butyl-8-methyl-2-thioxo-1-oxa-3,8-diaza-spiro[4.5]decan-4-one; hydrochloride::CHEMBL553865

SMILES: CN1CCC2(CC1)OC(=S)N(C2=O)C(C)(C)C

InChI Key: InChIKey=HGWKWDMGMRKIAK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50044692 (3-tert-Butyl-8-methyl-2-thioxo-1-oxa-3,8-diaza-spi...) Show SMILES CN1CCC2(CC1)OC(=S)N(C2=O)C(C)(C)C Show InChI InChI=1S/C12H20N2O2S/c1-11(2,3)14-9(15)12(16-10(14)17)5-7-13(4)8-6-12/h5-8H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Drug Discovery Research Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine from rat cortex membrane expressing muscarinic M1 receptor				J Med Chem 36: 2292-9 (1993) BindingDB Entry DOI: 10.7270/Q2W66MDV
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50044692 (3-tert-Butyl-8-methyl-2-thioxo-1-oxa-3,8-diaza-spi...) Show SMILES CN1CCC2(CC1)OC(=S)N(C2=O)C(C)(C)C Show InChI InChI=1S/C12H20N2O2S/c1-11(2,3)14-9(15)12(16-10(14)17)5-7-13(4)8-6-12/h5-8H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Drug Discovery Research Curated by ChEMBL					Assay Description Compound tested in vitro for displacement of [3H]quinuclidinyl benzilate from rat cerebellum membrane expressing muscarinic M2 receptor				J Med Chem 36: 2292-9 (1993) BindingDB Entry DOI: 10.7270/Q2W66MDV
					More data for this Ligand-Target Pair