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SMILES: CCN1C(=O)OC2(CCN(Cc3ccccc3)CC2)C1=O

InChI Key: InChIKey=JFZMJCQGIRHFOU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044699   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)		BDBM50044699
PNG
(8-Benzyl-3-ethyl-1-oxa-3,8-diaza-spiro[4.5]decane-...)
Show SMILES CCN1C(=O)OC2(CCN(Cc3ccccc3)CC2)C1=O
Show InChI InChI=1S/C16H20N2O3/c1-2-18-14(19)16(21-15(18)20)8-10-17(11-9-16)12-13-6-4-3-5-7-13/h3-7H,2,8-12H2,1H3
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PC sid
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PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Institute for Drug Discovery Research

Curated by ChEMBL


Assay Description
Displacement of [3H]pirenzepine from rat cortex membrane expressing muscarinic M1 receptor

J Med Chem 36: 2292-9 (1993)


BindingDB Entry DOI: 10.7270/Q2W66MDV
More data for this
Ligand-Target Pair