null
SMILES: Cc1cn(C2OC(COP(O)(=O)OCCCCCCCCC3CCC4C5CC=C6C[C@H](CCC6(C)C5CCC34C)OC=C)C=C2)c(=O)[nH]c1=O
InChI Key: InChIKey=SAKVGIJGJNARBV-ATKXQCLHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50044906 (CHEMBL353179 | Phosphoric acid 8-(10,13-dimethyl-3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
URA CNRS 1309 Curated by ChEMBL | Assay Description Effective concentration that reduces HIV-induced cytopathic effect by 50% was determined by reverse transcriptase (RT) assay. | J Med Chem 36: 826-30 (1993) BindingDB Entry DOI: 10.7270/Q2WW7JBD | |||||||||||
More data for this Ligand-Target Pair |