BDBM50044910 CHEMBL352398::Phosphoric acid bis-[5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl] ester
SMILES: Cc1cn(C2OC(COP(O)(=O)OCC3OC(C=C3)n3cc(C)c(=O)[nH]c3=O)C=C2)c(=O)[nH]c1=O
InChI Key: InChIKey=AFTUVCJBTTYRAU-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50044910 (CHEMBL352398 | Phosphoric acid bis-[5-(5-methyl-2,...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
URA CNRS 1309 Curated by ChEMBL | Assay Description Effective concentration that reduces HIV-induced cytopathic effect by 50% was determined by reverse transcriptase (RT) assay. | J Med Chem 36: 826-30 (1993) BindingDB Entry DOI: 10.7270/Q2WW7JBD | |||||||||||
More data for this Ligand-Target Pair |