Found 6 hits for monomerid = 50044955 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50044955
(CHEMBL3309402)Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(F)cc5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C38H33F2N5O5/c1-48-34-22-29-31(23-35(34)49-20-6-19-44-17-4-5-18-44)41-16-15-32(29)50-33-14-11-25(21-30(33)40)42-37(46)36-27-7-2-3-8-28(27)38(47)45(43-36)26-12-9-24(39)10-13-26/h2-3,7-16,21-23H,4-6,17-20H2,1H3,(H,42,46) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrate |
Bioorg Med Chem 22: 3642-53 (2014)
Article DOI: 10.1016/j.bmc.2014.05.013
BindingDB Entry DOI: 10.7270/Q23T9JV2 |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50044955
(CHEMBL3309402)Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(F)cc5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C38H33F2N5O5/c1-48-34-22-29-31(23-35(34)49-20-6-19-44-17-4-5-18-44)41-16-15-32(29)50-33-14-11-25(21-30(33)40)42-37(46)36-27-7-2-3-8-28(27)38(47)45(43-36)26-12-9-24(39)10-13-26/h2-3,7-16,21-23H,4-6,17-20H2,1H3,(H,42,46) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University
Curated by ChEMBL
| Assay Description
Inhibition of c-KIT (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrate |
Bioorg Med Chem 22: 3642-53 (2014)
Article DOI: 10.1016/j.bmc.2014.05.013
BindingDB Entry DOI: 10.7270/Q23T9JV2 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50044955
(CHEMBL3309402)Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(F)cc5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C38H33F2N5O5/c1-48-34-22-29-31(23-35(34)49-20-6-19-44-17-4-5-18-44)41-16-15-32(29)50-33-14-11-25(21-30(33)40)42-37(46)36-27-7-2-3-8-28(27)38(47)45(43-36)26-12-9-24(39)10-13-26/h2-3,7-16,21-23H,4-6,17-20H2,1H3,(H,42,46) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrate |
Bioorg Med Chem 22: 3642-53 (2014)
Article DOI: 10.1016/j.bmc.2014.05.013
BindingDB Entry DOI: 10.7270/Q23T9JV2 |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50044955
(CHEMBL3309402)Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(F)cc5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C38H33F2N5O5/c1-48-34-22-29-31(23-35(34)49-20-6-19-44-17-4-5-18-44)41-16-15-32(29)50-33-14-11-25(21-30(33)40)42-37(46)36-27-7-2-3-8-28(27)38(47)45(43-36)26-12-9-24(39)10-13-26/h2-3,7-16,21-23H,4-6,17-20H2,1H3,(H,42,46) | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRalpha (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrate |
Bioorg Med Chem 22: 3642-53 (2014)
Article DOI: 10.1016/j.bmc.2014.05.013
BindingDB Entry DOI: 10.7270/Q23T9JV2 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50044955
(CHEMBL3309402)Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(F)cc5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C38H33F2N5O5/c1-48-34-22-29-31(23-35(34)49-20-6-19-44-17-4-5-18-44)41-16-15-32(29)50-33-14-11-25(21-30(33)40)42-37(46)36-27-7-2-3-8-28(27)38(47)45(43-36)26-12-9-24(39)10-13-26/h2-3,7-16,21-23H,4-6,17-20H2,1H3,(H,42,46) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrate |
Bioorg Med Chem 22: 3642-53 (2014)
Article DOI: 10.1016/j.bmc.2014.05.013
BindingDB Entry DOI: 10.7270/Q23T9JV2 |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50044955
(CHEMBL3309402)Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(F)cc5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C38H33F2N5O5/c1-48-34-22-29-31(23-35(34)49-20-6-19-44-17-4-5-18-44)41-16-15-32(29)50-33-14-11-25(21-30(33)40)42-37(46)36-27-7-2-3-8-28(27)38(47)45(43-36)26-12-9-24(39)10-13-26/h2-3,7-16,21-23H,4-6,17-20H2,1H3,(H,42,46) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrate |
Bioorg Med Chem 22: 3642-53 (2014)
Article DOI: 10.1016/j.bmc.2014.05.013
BindingDB Entry DOI: 10.7270/Q23T9JV2 |
More data for this
Ligand-Target Pair | |
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