BDBM50045038 CHEMBL3310395

SMILES: OC(=O)[C@@H](NC(=O)Cc1csc(n1)-c1ncc(cc1O)C#N)c1ccccc1

InChI Key: InChIKey=KPGRSPXHOOAVBE-INIZCTEOSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50045038 (CHEMBL3310395) Show SMILES OC(=O)[C@@H](NC(=O)Cc1csc(n1)-c1ncc(cc1O)C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H14N4O4S/c20-8-11-6-14(24)17(21-9-11)18-22-13(10-28-18)7-15(25)23-16(19(26)27)12-4-2-1-3-5-12/h1-6,9-10,16,24H,7H2,(H,23,25)(H,26,27)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of PHD2 in human Hep3B cells assessed as erythropoietin secretion by ELISA				Bioorg Med Chem Lett 24: 3142-5 (2014) Article DOI: 10.1016/j.bmcl.2014.05.003 BindingDB Entry DOI: 10.7270/Q2QN68F3
					More data for this Ligand-Target Pair				3D Structure (crystal)