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BDBM50045845 CHEMBL3314351

SMILES: CN(C)Cc1ccc2CN(CCc2c1)C(=O)c1cc2ccncc2n1C

InChI Key: InChIKey=VEHHSNLPCDSQJA-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045845   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GPR103


(Homo sapiens (Human))
BDBM50045845
PNG
(CHEMBL3314351)
Show SMILES CN(C)Cc1ccc2CN(CCc2c1)C(=O)c1cc2ccncc2n1C
Show InChI InChI=1S/C21H24N4O/c1-23(2)13-15-4-5-18-14-25(9-7-16(18)10-15)21(26)19-11-17-6-8-22-12-20(17)24(19)3/h4-6,8,10-12H,7,9,13-14H2,1-3H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assay


J Med Chem 57: 5935-48 (2014)


Article DOI: 10.1021/jm401951t
BindingDB Entry DOI: 10.7270/Q2MP54W9
More data for this
Ligand-Target Pair