BDBM50045865 2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethanone::CHEMBL100029

SMILES: O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1

InChI Key: InChIKey=GFRHLCDSWKISNK-UHFFFAOYSA-N

Data: 1 KI  8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50045865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
CCKBR (RAT)	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Opioid receptor (Rattus norvegicus (rat)-RAT)	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Opioid receptor (Rattus norvegicus (rat)-RAT)	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]naxolone binding to opiate receptors in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Adrenergic receptor alpha (Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Adrenergic receptor alpha (Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Adrenergic receptor beta (Rattus norvegicus (Rat))	BDBM50045865 (2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...) Show SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c24-20(23-13-7-2-8-14-23)15-18-17-11-5-6-12-19(17)22-21(18)16-9-3-1-4-10-16/h1,3-6,9-12,22H,2,7-8,13-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair