BDBM50046047 CHEMBL3310140

SMILES: Fc1ccc(cc1)-c1noc(NC(=O)Cc2ccccc2F)c1-c1ccncn1

InChI Key: InChIKey=KBVXEKXREZLSND-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50046047 (CHEMBL3310140) Show SMILES Fc1ccc(cc1)-c1noc(NC(=O)Cc2ccccc2F)c1-c1ccncn1 Show InChI InChI=1S/C21H14F2N4O2/c22-15-7-5-13(6-8-15)20-19(17-9-10-24-12-25-17)21(29-27-20)26-18(28)11-14-3-1-2-4-16(14)23/h1-10,12H,11H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
ASKA Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of full length human p38alpha MAP kinase by Off-chip mobility shift assay				Bioorg Med Chem 22: 4162-76 (2014) Article DOI: 10.1016/j.bmc.2014.05.045 BindingDB Entry DOI: 10.7270/Q2C82BXS
					More data for this Ligand-Target Pair