BDBM50046047 CHEMBL3310140
SMILES: Fc1ccc(cc1)-c1noc(NC(=O)Cc2ccccc2F)c1-c1ccncn1
InChI Key: InChIKey=KBVXEKXREZLSND-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50046047 (CHEMBL3310140) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
ASKA Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of full length human p38alpha MAP kinase by Off-chip mobility shift assay | Bioorg Med Chem 22: 4162-76 (2014) Article DOI: 10.1016/j.bmc.2014.05.045 BindingDB Entry DOI: 10.7270/Q2C82BXS | |||||||||||
More data for this Ligand-Target Pair |