BDBM50046053 CHEMBL3310146

SMILES: Fc1ccc(-c2noc(NC(=O)Cc3ccccc3Cl)c2-c2ccncn2)c(F)c1

InChI Key: InChIKey=QOGGUCJFELPAEY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50046053 (CHEMBL3310146) Show SMILES Fc1ccc(-c2noc(NC(=O)Cc3ccccc3Cl)c2-c2ccncn2)c(F)c1 Show InChI InChI=1S/C21H13ClF2N4O2/c22-15-4-2-1-3-12(15)9-18(29)27-21-19(17-7-8-25-11-26-17)20(28-30-21)14-6-5-13(23)10-16(14)24/h1-8,10-11H,9H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
ASKA Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of full length human p38alpha MAP kinase by Off-chip mobility shift assay				Bioorg Med Chem 22: 4162-76 (2014) Article DOI: 10.1016/j.bmc.2014.05.045 BindingDB Entry DOI: 10.7270/Q2C82BXS
					More data for this Ligand-Target Pair