BDBM50046056 CHEMBL3310149

SMILES: Cc1cccc(c1)-c1noc(NC(=O)Cc2ccccc2Cl)c1-c1ccncn1

InChI Key: InChIKey=BWJBUFSDWGGBFI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50046056 (CHEMBL3310149) Show SMILES Cc1cccc(c1)-c1noc(NC(=O)Cc2ccccc2Cl)c1-c1ccncn1 Show InChI InChI=1S/C22H17ClN4O2/c1-14-5-4-7-16(11-14)21-20(18-9-10-24-13-25-18)22(29-27-21)26-19(28)12-15-6-2-3-8-17(15)23/h2-11,13H,12H2,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
ASKA Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of full length human p38alpha MAP kinase by Off-chip mobility shift assay				Bioorg Med Chem 22: 4162-76 (2014) Article DOI: 10.1016/j.bmc.2014.05.045 BindingDB Entry DOI: 10.7270/Q2C82BXS
					More data for this Ligand-Target Pair