BDBM50046105 CHEMBL3310843

SMILES: Cc1cccc(NNS(=O)(=O)c2ccc(cc2)S(C)(=O)=O)c1

InChI Key: InChIKey=NPMKLJOJVTWKPA-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50046105 (CHEMBL3310843) Show SMILES Cc1cccc(NNS(=O)(=O)c2ccc(cc2)S(C)(=O)=O)c1 Show InChI InChI=1S/C14H16N2O4S2/c1-11-4-3-5-12(10-11)15-16-22(19,20)14-8-6-13(7-9-14)21(2,17)18/h3-10,15-16H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.85E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50046105 (CHEMBL3310843) Show SMILES Cc1cccc(NNS(=O)(=O)c2ccc(cc2)S(C)(=O)=O)c1 Show InChI InChI=1S/C14H16N2O4S2/c1-11-4-3-5-12(10-11)15-16-22(19,20)14-8-6-13(7-9-14)21(2,17)18/h3-10,15-16H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in Escherichia coli using N-formylkynurenine as substrate incubated for 1 hr prior to NaOH addition mea...				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair