BDBM50046146 CHEMBL3310980

SMILES: OC(=O)COc1ccc(cc1)S(=O)(=O)NNc1ccc(Br)cc1

InChI Key: InChIKey=JRANKDFHLDTFGH-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50046146 (CHEMBL3310980) Show SMILES OC(=O)COc1ccc(cc1)S(=O)(=O)NNc1ccc(Br)cc1 Show InChI InChI=1S/C14H13BrN2O5S/c15-10-1-3-11(4-2-10)16-17-23(20,21)13-7-5-12(6-8-13)22-9-14(18)19/h1-8,16-17H,9H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	152	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50046146 (CHEMBL3310980) Show SMILES OC(=O)COc1ccc(cc1)S(=O)(=O)NNc1ccc(Br)cc1 Show InChI InChI=1S/C14H13BrN2O5S/c15-10-1-3-11(4-2-10)16-17-23(20,21)13-7-5-12(6-8-13)22-9-14(18)19/h1-8,16-17H,9H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in Escherichia coli using N-formylkynurenine as substrate incubated for 1 hr prior to NaOH addition mea...				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair