null

SMILES: CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1cccc(Br)c1

InChI Key: InChIKey=KAUXONHHBVMJGN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50046157 (CHEMBL3310856) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1cccc(Br)c1 Show InChI InChI=1S/C14H14BrN3O3S/c1-10(19)16-12-5-7-14(8-6-12)22(20,21)18-17-13-4-2-3-11(15)9-13/h2-9,17-18H,1H3,(H,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.56E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50046157 (CHEMBL3310856) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1cccc(Br)c1 Show InChI InChI=1S/C14H14BrN3O3S/c1-10(19)16-12-5-7-14(8-6-12)22(20,21)18-17-13-4-2-3-11(15)9-13/h2-9,17-18H,1H3,(H,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	255	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in Escherichia coli using N-formylkynurenine as substrate incubated for 1 hr prior to NaOH addition mea...				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair