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SMILES: Nc1nc2nc(Cc3ccsc3)[nH]c2c(=O)[nH]1

InChI Key: InChIKey=NSMPJAYXYKAEJY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046254   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Purine nucleoside phosphorylase


(Homo sapiens (Human))		BDBM50046254
PNG
(2-Amino-8-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)
Show SMILES Nc1nc2nc(Cc3ccsc3)[nH]c2c(=O)[nH]1
Show InChI InChI=1S/C10H9N5OS/c11-10-14-8-7(9(16)15-10)12-6(13-8)3-5-1-2-17-4-5/h1-2,4H,3H2,(H4,11,12,13,14,15,16)
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n/an/a 11n/an/an/an/an/an/a



BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphate

J Med Chem 36: 55-69 (1993)


BindingDB Entry DOI: 10.7270/Q2B27TCX
More data for this
Ligand-Target Pair