BDBM50046255 2-Amino-8-(pyridin-3-ylamino)-1,9-dihydro-purin-6-one::CHEMBL159266

SMILES: Nc1nc2nc(Nc3cccnc3)[nH]c2c(=O)[nH]1

InChI Key: InChIKey=AZRLNXMWWUPIGP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50046255 (2-Amino-8-(pyridin-3-ylamino)-1,9-dihydro-purin-6-...) Show SMILES Nc1nc2nc(Nc3cccnc3)[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C10H9N7O/c11-9-15-7-6(8(18)17-9)14-10(16-7)13-5-2-1-3-12-4-5/h1-4H,(H5,11,13,14,15,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphate				J Med Chem 36: 55-69 (1993) BindingDB Entry DOI: 10.7270/Q2B27TCX
					More data for this Ligand-Target Pair