BDBM50046350 1-(4-Cyclohexyl-4-oxo-butyryl)-pyrrolidine-2-carboxylic acid (1-formyl-4-guanidino-butyl)-amide::CHEMBL317878

SMILES: NC(=N)NCCCC(NC(=O)C1CCCN1C(=O)C(=O)CCC1CCCCC1)C=O

InChI Key: InChIKey=RMAGJLSQVUAQJP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50046350 (1-(4-Cyclohexyl-4-oxo-butyryl)-pyrrolidine-2-carbo...) Show SMILES NC(=N)NCCCC(NC(=O)C1CCCN1C(=O)C(=O)CCC1CCCCC1)C=O Show InChI InChI=1S/C21H35N5O4/c22-21(23)24-12-4-8-16(14-27)25-19(29)17-9-5-13-26(17)20(30)18(28)11-10-15-6-2-1-3-7-15/h14-17H,1-13H2,(H,25,29)(H4,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Concentration required to inhibit thrombin hydrolysis of the chromogenic substrate				J Med Chem 36: 300-3 (1993) BindingDB Entry DOI: 10.7270/Q2JM28Q8
					More data for this Ligand-Target Pair