BDBM50046748 2-(6-Amino-purin-9-yl)-5-fluoromethylene-tetrahydro-furan-3,4-diol::CHEMBL171369
SMILES: Nc1ncnc2n(cnc12)[C@@H]1O\C(=C\F)[C@H](O)[C@@H]1O
InChI Key: InChIKey=NAWIFPQLACUTSO-DSZYPIRLSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosylhomocysteinase (Rattus norvegicus) | BDBM50046748 (2-(6-Amino-purin-9-yl)-5-fluoromethylene-tetrahydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibitory activity against recombinant rat liver S-adenosyl-homocysteine hydrolase | J Med Chem 36: 883-7 (1993) BindingDB Entry DOI: 10.7270/Q2HM593F | |||||||||||
More data for this Ligand-Target Pair |