BDBM50046864 6-(2,8-Diamino-6-oxo-1,6-dihydro-purin-9-yl)-hexanoic acid::CHEMBL8246

SMILES: Nc1nc2c(nc(N)[nH]c2=O)n1CCCCCC(O)=O

InChI Key: InChIKey=PBVBVXPCRZXJMQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50046864 (6-(2,8-Diamino-6-oxo-1,6-dihydro-purin-9-yl)-hexan...) Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1CCCCCC(O)=O Show InChI InChI=1S/C11H16N6O3/c12-10-15-8-7(9(20)16-10)14-11(13)17(8)5-3-1-2-4-6(18)19/h1-5H2,(H2,13,14)(H,18,19)(H3,12,15,16,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Defense Medical Center Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against PNP activity in dialyzed extracts from human erythrocytes				J Med Chem 36: 1024-31 (1993) BindingDB Entry DOI: 10.7270/Q2CV4JCQ
					More data for this Ligand-Target Pair