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SMILES: CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(ccc3Cl)-n3cccc3)sc2c1

InChI Key: InChIKey=JZNJIBSGZUYYIU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047677   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM50047677
PNG
(CHEMBL3319282)
Show SMILES CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(ccc3Cl)-n3cccc3)sc2c1
Show InChI InChI=1S/C20H15ClN4O4S2/c1-31(28,29)13-5-7-16-17(11-13)30-20(22-16)24-19(27)23-18(26)14-10-12(4-6-15(14)21)25-8-2-3-9-25/h2-11H,1H3,(H2,22,23,24,26,27)
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n/an/a 23n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method

J Med Chem 57: 6128-40 (2014)


Article DOI: 10.1021/jm500610n
BindingDB Entry DOI: 10.7270/Q279469X
More data for this
Ligand-Target Pair