BDBM50047962 CHEMBL1966136
SMILES: [O-][N+](=O)c1cc(c(\C=C\c2ccc(Cl)c(Cl)c2)cc1\C=C\c1ccc(Cl)c(Cl)c1)[N+]([O-])=O
InChI Key: InChIKey=YYZPXBXVBQSBDG-IJIVKGSJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 4B (Homo sapiens (Human)) | BDBM50047962 (CHEMBL1966136) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Tsing-Hua University Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human KDM4B (1 to 348 aa) expressed in Escherichia coli using H3K9me3 peptide as substrate after 30 mins by dou... | J Med Chem 57: 5975-85 (2014) Article DOI: 10.1021/jm500249n BindingDB Entry DOI: 10.7270/Q2QC0557 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4A (KDM4A) (Homo sapiens (Human)) | BDBM50047962 (CHEMBL1966136) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Tsing-Hua University Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human KDM4A (1 to 347 aa) expressed in Escherichia coli using H3K9me3 peptide as substrate after 30 mins by dou... | J Med Chem 57: 5975-85 (2014) Article DOI: 10.1021/jm500249n BindingDB Entry DOI: 10.7270/Q2QC0557 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4B (Homo sapiens (Human)) | BDBM50047962 (CHEMBL1966136) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Tsing-Hua University Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human KDM4B (1 to 348 aa) expressed in Escherichia coli using H3K9me3 (3 to 17 aa) peptide as substrate after 3... | J Med Chem 57: 5975-85 (2014) Article DOI: 10.1021/jm500249n BindingDB Entry DOI: 10.7270/Q2QC0557 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4A (KDM4A) (Homo sapiens (Human)) | BDBM50047962 (CHEMBL1966136) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Tsing-Hua University Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human KDM4A (1 to 347 aa) expressed in Escherichia coli using H3K9me3 (3 to 17 aa) peptide as substrate after 3... | J Med Chem 57: 5975-85 (2014) Article DOI: 10.1021/jm500249n BindingDB Entry DOI: 10.7270/Q2QC0557 | |||||||||||
More data for this Ligand-Target Pair |