BDBM50048189 4-(6-Methanesulfonylamino-3-oxo-indan-5-ylsulfanyl)-benzoic acid::CHEMBL145783

SMILES: CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(cc1)C(O)=O

InChI Key: InChIKey=NHNVMDXHFDMOPP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048189 (4-(6-Methanesulfonylamino-3-oxo-indan-5-ylsulfanyl...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(cc1)C(O)=O Show InChI InChI=1S/C17H15NO5S2/c1-25(22,23)18-14-8-11-4-7-15(19)13(11)9-16(14)24-12-5-2-10(3-6-12)17(20)21/h2-3,5-6,8-9,18H,4,7H2,1H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair