BDBM50048197 CHEMBL143781::N-[6-(2,6-Difluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1c(F)cccc1F

InChI Key: InChIKey=YOULWLUHEYHUJF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048197 (CHEMBL143781 | N-[6-(2,6-Difluoro-phenylsulfanyl)-...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1c(F)cccc1F Show InChI InChI=1S/C16H13F2NO3S2/c1-24(21,22)19-13-7-9-5-6-14(20)10(9)8-15(13)23-16-11(17)3-2-4-12(16)18/h2-4,7-8,19H,5-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50048197 (CHEMBL143781 | N-[6-(2,6-Difluoro-phenylsulfanyl)-...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1c(F)cccc1F Show InChI InChI=1S/C16H13F2NO3S2/c1-24(21,22)19-13-7-9-5-6-14(20)10(9)8-15(13)23-16-11(17)3-2-4-12(16)18/h2-4,7-8,19H,5-6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1 in human U937 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair