BDBM50048203 CHEMBL357918::Ethanesulfonic acid [6-(2,4-difluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-amide

SMILES: CCS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(F)cc1F

InChI Key: InChIKey=CJBZZVYTXKNPNY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048203 (CHEMBL357918 | Ethanesulfonic acid [6-(2,4-difluor...) Show SMILES CCS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(F)cc1F Show InChI InChI=1S/C17H15F2NO3S2/c1-2-25(22,23)20-14-7-10-3-5-15(21)12(10)9-17(14)24-16-6-4-11(18)8-13(16)19/h4,6-9,20H,2-3,5H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50048203 (CHEMBL357918 | Ethanesulfonic acid [6-(2,4-difluor...) Show SMILES CCS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(F)cc1F Show InChI InChI=1S/C17H15F2NO3S2/c1-2-25(22,23)20-14-7-10-3-5-15(21)12(10)9-17(14)24-16-6-4-11(18)8-13(16)19/h4,6-9,20H,2-3,5H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1 in human U937 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair