BDBM50048205 CHEMBL343889::N-[6-(2,4-Difluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-acetamide

SMILES: CC(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(F)cc1F

InChI Key: InChIKey=UCPOVVIALHLMED-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048205 (CHEMBL343889 | N-[6-(2,4-Difluoro-phenylsulfanyl)-...) Show SMILES CC(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(F)cc1F Show InChI InChI=1S/C17H13F2NO2S/c1-9(21)20-14-6-10-2-4-15(22)12(10)8-17(14)23-16-5-3-11(18)7-13(16)19/h3,5-8H,2,4H2,1H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair