BDBM50048214 CHEMBL144675::N-(1-Oxo-6-o-tolylsulfanyl-indan-5-yl)-methanesulfonamide

SMILES: Cc1ccccc1Sc1cc2C(=O)CCc2cc1NS(C)(=O)=O

InChI Key: InChIKey=LZIOBQUCZYZXLW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048214 (CHEMBL144675 | N-(1-Oxo-6-o-tolylsulfanyl-indan-5-...) Show SMILES Cc1ccccc1Sc1cc2C(=O)CCc2cc1NS(C)(=O)=O Show InChI InChI=1S/C17H17NO3S2/c1-11-5-3-4-6-16(11)22-17-10-13-12(7-8-15(13)19)9-14(17)18-23(2,20)21/h3-6,9-10,18H,7-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50048214 (CHEMBL144675 | N-(1-Oxo-6-o-tolylsulfanyl-indan-5-...) Show SMILES Cc1ccccc1Sc1cc2C(=O)CCc2cc1NS(C)(=O)=O Show InChI InChI=1S/C17H17NO3S2/c1-11-5-3-4-6-16(11)22-17-10-13-12(7-8-15(13)19)9-14(17)18-23(2,20)21/h3-6,9-10,18H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1 in human U937 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair