BDBM50048215 CHEMBL357163::N-[6-(4-tert-Butyl-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES: CC(C)(C)c1ccc(Sc2cc3C(=O)CCc3cc2NS(C)(=O)=O)cc1

InChI Key: InChIKey=ROUOARWIXRCSQJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048215 (CHEMBL357163 | N-[6-(4-tert-Butyl-phenylsulfanyl)-...) Show SMILES CC(C)(C)c1ccc(Sc2cc3C(=O)CCc3cc2NS(C)(=O)=O)cc1 Show InChI InChI=1S/C20H23NO3S2/c1-20(2,3)14-6-8-15(9-7-14)25-19-12-16-13(5-10-18(16)22)11-17(19)21-26(4,23)24/h6-9,11-12,21H,5,10H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair