BDBM50048216 CHEMBL144013::N-[6-(2,4-Difluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-C,C,C-trifluoro-methanesulfonamide

SMILES: Fc1ccc(Sc2cc3C(=O)CCc3cc2NS(=O)(=O)C(F)(F)F)c(F)c1

InChI Key: InChIKey=SBRPEJRFRRXYSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048216 (CHEMBL144013 | N-[6-(2,4-Difluoro-phenylsulfanyl)-...) Show SMILES Fc1ccc(Sc2cc3C(=O)CCc3cc2NS(=O)(=O)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C16H10F5NO3S2/c17-9-2-4-14(11(18)6-9)26-15-7-10-8(1-3-13(10)23)5-12(15)22-27(24,25)16(19,20)21/h2,4-7,22H,1,3H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair