BDBM50048257 CHEMBL3310770

SMILES: CS(=O)(=O)Nc1nc(SCc2cccc(F)c2F)nc(-c2ccccc2)c1C#N

InChI Key: InChIKey=VEIJYXBZJLBHIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50048257 (CHEMBL3310770) Show SMILES CS(=O)(=O)Nc1nc(SCc2cccc(F)c2F)nc(-c2ccccc2)c1C#N Show InChI InChI=1S/C19H14F2N4O2S2/c1-29(26,27)25-18-14(10-22)17(12-6-3-2-4-7-12)23-19(24-18)28-11-13-8-5-9-15(20)16(13)21/h2-9H,11H2,1H3,(H,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity against human recombinant CXCR2 receptor expressed in CHO cell membranes by SPA based [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 24: 3285-90 (2014) Article DOI: 10.1016/j.bmcl.2014.06.011 BindingDB Entry DOI: 10.7270/Q2930VTJ
					More data for this Ligand-Target Pair