BDBM50048323 (S)-3-(4-Hydroxy-phenyl)-2-{[2-((S)-2-mercapto-3-methyl-butyrylamino)-bicyclo[2.2.1]heptane-2-carbonyl]-amino}-propionic acid::CHEMBL148368

SMILES: CC(C)[C@H](S)C(=O)NC1(CC2CCC1C2)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI Key: InChIKey=DLLWEEYOIQTAHB-PIUDKDNESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50048323 ((S)-3-(4-Hydroxy-phenyl)-2-{[2-((S)-2-mercapto-3-m...) Show SMILES CC(C)[C@H](S)C(=O)NC1(CC2CCC1C2)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |TLB:15:8:14:12.11,THB:7:8:14:12.11| Show InChI InChI=1S/C22H30N2O5S/c1-12(2)18(30)19(26)24-22(11-14-3-6-15(22)9-14)21(29)23-17(20(27)28)10-13-4-7-16(25)8-5-13/h4-5,7-8,12,14-15,17-18,25,30H,3,6,9-11H2,1-2H3,(H,23,29)(H,24,26)(H,27,28)/t14?,15?,17-,18-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Evaluation of in vitro inhibitory activity against Neutral endopeptidase				J Med Chem 38: 5023-30 (1996) BindingDB Entry DOI: 10.7270/Q26D5TMH
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50048323 ((S)-3-(4-Hydroxy-phenyl)-2-{[2-((S)-2-mercapto-3-m...) Show SMILES CC(C)[C@H](S)C(=O)NC1(CC2CCC1C2)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |TLB:15:8:14:12.11,THB:7:8:14:12.11| Show InChI InChI=1S/C22H30N2O5S/c1-12(2)18(30)19(26)24-22(11-14-3-6-15(22)9-14)21(29)23-17(20(27)28)10-13-4-7-16(25)8-5-13/h4-5,7-8,12,14-15,17-18,25,30H,3,6,9-11H2,1-2H3,(H,23,29)(H,24,26)(H,27,28)/t14?,15?,17-,18-,22?/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Evaluation of in vitro inhibitory activity against Angiotensin I converting enzyme				J Med Chem 38: 5023-30 (1996) BindingDB Entry DOI: 10.7270/Q26D5TMH
					More data for this Ligand-Target Pair