BDBM50048373 CHEMBL3310150
SMILES: Nc1nc2c3c(NCCO)cccc3nc(Cc3ccc4OCOc4c3)n2n1
InChI Key: InChIKey=CVMXDRJFHVAAAN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50048373 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Heat shock protein HSP 90-beta
(Homo sapiens (Human)) | BDBM50048373
(CHEMBL3310150)Show InChI InChI=1S/C19H18N6O3/c20-19-23-18-17-12(21-6-7-26)2-1-3-13(17)22-16(25(18)24-19)9-11-4-5-14-15(8-11)28-10-27-14/h1-5,8,21,26H,6-7,9-10H2,(H2,20,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of Hsp90 (unknown origin) by FP displacement assay |
Bioorg Med Chem 22: 4135-50 (2014)
Article DOI: 10.1016/j.bmc.2014.05.056
BindingDB Entry DOI: 10.7270/Q2S46TMD |
More data for this
Ligand-Target Pair | |
Heat shock protein HSP 90-beta
(Homo sapiens (Human)) | BDBM50048373
(CHEMBL3310150)Show InChI InChI=1S/C19H18N6O3/c20-19-23-18-17-12(21-6-7-26)2-1-3-13(17)22-16(25(18)24-19)9-11-4-5-14-15(8-11)28-10-27-14/h1-5,8,21,26H,6-7,9-10H2,(H2,20,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of Hsp90 (unknown origin) by NMR FAXS screening method |
Bioorg Med Chem 22: 4135-50 (2014)
Article DOI: 10.1016/j.bmc.2014.05.056
BindingDB Entry DOI: 10.7270/Q2S46TMD |
More data for this
Ligand-Target Pair | |
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