BDBM50048815 2-[5-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pentyl]-2,3-dihydro-isoindol-1-one::CHEMBL41636

SMILES: O=C1N(CCCCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12

InChI Key: InChIKey=DODCYUIQFWNTQY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048815 (2-[5-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pe...) Show SMILES O=C1N(CCCCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 Show InChI InChI=1S/C24H28N4OS/c29-24-20-9-3-2-8-19(20)18-28(24)13-7-1-6-12-26-14-16-27(17-15-26)23-21-10-4-5-11-22(21)30-25-23/h2-5,8-11H,1,6-7,12-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding at serotonin 5-hydroxytryptamine 1A receptor from rat hippocampus tissue.				J Med Chem 39: 149-57 (1996) Article DOI: 10.1021/jm9502201 BindingDB Entry DOI: 10.7270/Q2TQ60MN
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50048815 (2-[5-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pe...) Show SMILES O=C1N(CCCCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 Show InChI InChI=1S/C24H28N4OS/c29-24-20-9-3-2-8-19(20)18-28(24)13-7-1-6-12-26-14-16-27(17-15-26)23-21-10-4-5-11-22(21)30-25-23/h2-5,8-11H,1,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-raclopride binding at Dopamine receptor D2 from rat striata.				J Med Chem 39: 149-57 (1996) Article DOI: 10.1021/jm9502201 BindingDB Entry DOI: 10.7270/Q2TQ60MN
					More data for this Ligand-Target Pair